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An allergy is an immunological hypersensitivity mediated by immunoglobulin E antibody (IgE).

An allergy is an immunological hypersensitivity mediated by immunoglobulin E antibody (IgE). It is not related to any disease or infections.

Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues.

An autoimmune disease is said to be present when the immune system mistakenly attacks the body.

Typically, autoimmunity can involve the following diseases such as rheumatoid arthritis, inflammatory bowel movement and multiple sclerosis

Allergies and autoimmunity are conditions related to the immune system. Allergies are reactions which are brought about when the immune system reacts to foreign substances in the environment. Autoimmunity is a system of responses from the immune system against the body’s healthy cells and tissues.

An allergy is an immunological hypersensitivity mediated by immunoglobulin E antibody (IgE). It is not related to any disease or infections. Allergies can be seen in many organs, but most commonly, they affect the skin and mucous membranes. Our body is sensitive to specific particles in the environment, and these particles are called allergens. Allergies are mostly a type of antigen that produces an abnormally vigorous immune response. Certain features of allergies are explained below:

Autoimmunity is the system of immune responses of an organism against its healthy cells and tissues. A disease which results due to this kind of response is called an autoimmune disease. The higher vertebrates are capable of recognising foreign antigens. Due to the memory-based acquired immunity, their immune system could very well distinguish between its cells and the foreign organisms. However, due to a genetic condition or some other unknown reason, the body attacks its own cells. The resulting diseases are called autoimmune diseases. The most common example of an autoimmune disease is  rheumatoid arthritis  (RA). Others are Addison’s disease, Graves’ disease, polymyositis (PM), etc.

The main similarities between the two are as follows:

The main difference between autoimmune diseases and allergies are summarised in the table as follows:

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A condition in which the immune system reacts abnormally to a foreign substance.

An autoimmune disease is a condition in which the immune system mistakenly attacks healthy cells and tissues of the body.

The allergies are mainly caused by an external trigger such as pollens, certain foods, medicines, insects, animals, etc.

Autoimmune diseases are the results of an internal trigger to the body’s own cell.

Examples include skin allergy, sinusitis, asthma, watery eyes, sneezing, itchy nose and eyes.

Examples include type 1 diabetes, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, etc.